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FNDC5 variant irisin links exercise to brain health and may slow Alzheimer’s and Parkinson’s disease

in medicine

A new finding suggests that the protein FNDC5 or its variant irisin is imporatant in brain health following exercise and may slow the progression of neurogenerative diseases such as Alzheimer's disease and Parkinson's disease.  

Vesicle transport gets Nobel Prize for Medicine.

in medicine, biology

The work of three scientists, Randy W. Schekman, Thomas C. Südhof and James E. Rothman,  gave us insight into the role of vesicles and vesicular transport in health and disease.

Lifespan Extension by Red Wine Ingredient Resveratrol Linked to Methylation Following Action on SirT1

in medicine, biology

A new research suggests that the protein target of the red wine ingredient resveratrol may be extending lifespan by a new mechanism.  The protein target of resveratrol in mammals is the enzyme called SirT1, which belongs to a family of proteins called sirtuins.

Genome-wide meta-analysis identifies new loci and candidate genes for migraine

in medicine, omics

A research team has identified 12 genetic regions associated with migraine susceptibility using a large-scale genome study. Eight of these regions related to migraine were found in or near genes known to play a role in controlling brain circuitries and two of the regions were associated with genes that are responsible for maintaining healthy brain tissue.

Septin important in T cell calcium channel activation and T cell survival and activation - new study

in medicine

Researchers report that a certain type of protein called septins  play a critical role in activating a calcium channel on the surface of the T cell. The channel is the membrane door through which calcium enters T cells, an action essential for the T cell's survival, activation, and ability to fight disease.

Alzheimer's disease protein beta-secretase may also control movement

in medicine

Researchers have revealed that, beta-secretase, a protein known for its role in Alzheimer's disease controls spindle development in muscle and leads to impaired movement in mice when the protein is absent or treated with inhibitors. 

Axon pruning: How neurons amputate their axons

in medicine, biology

A new study details the mechanism by which axon pruning takes place.  The scientists say that neurons amputate their axons, axon pruning, by a process similar to a cell death process called apoptosis. An axon is a long tail-like projection of a cell body that transmits information to other neurons or muscles.

Fish oil protects heart from mental stress – the omega 3 fatty acid secret revealed

in medicine

A new study by scientists at the Michigan Technological University suggests that fish oil might alleviate the bad effects of mental stress on the heart.   The omega 3 fatty acids in fish oil have long been thought to protect against heart diseases.